From Ross-Tech Wiki

4.13 Does VAG-COM work with cars that require direct CAN access for diagnostics?
Yes! We have integrated CAN compatibility into Release 404.0 and newer versions of VAG-COM, but since CAN uses different hardware, new interfaces are required. These are now available as well. The HEX-COM+CAN and HEX-USB+CAN interfaces are fully compatible with the new latest cars which require a direct CAN connection.